| MID-ATLANTIC DIVISION | GP | W | L | T | PTS | GF | GA | GF | GD | |
| Reading United AC | 4 | 4 | 0 | 0 | 12 | 13 | 1 | 10 | +9 | |
| Ironbound Express | 4 | 4 | 0 | 0 | 12 | 9 | 0 | 9 | +9 | |
| New Jersey Rangers | 4 | 3 | 1 | 0 | 9 | 7 | 3 | 7 | +4 | |
| Carolina Dynamo | 4 | 2 | 1 | 1 | 7 | 11 | 7 | 7 | +3 | |
| Central Jersey Spartans | 4 | 1 | 2 | 1 | 4 | 3 | 6 | 3 | -3 | |
| West Virginia Chaos | 4 | 1 | 3 | 0 | 3 | 2 | 7 | 2 | -5 | |
| Ocean City Nor’easters | 4 | 0 | 2 | 2 | 2 | 4 | 8 | 4 | -4 | |
| Northern Virginia Royals | 4 | 0 | 3 | 1 | 1 | 5 | 13 | 5 | -6 | |
| Hampton Roads Piranhas | 4 | 0 | 3 | 1 | 1 | 3 | 12 | 3 | -7 |
Top team qualifies for the US Open Cup
Clinched Open Cup berth – Eliminated from contention
Note: Columns on the far right are for tiebreaker purposes
USL Premier Development League tiebreakers
(1) Head-to-head record based on total points in Open Cup qualifiers
(2) Total wins in Open Cup qualifying games
(3) Goal difference (+/- 3 goals maximum for each USOC qualifier)
(4) Goals scored (+/- 3 goals maximum for each USOC qualifier)
(5) Lottery conducted by the USL
All times Eastern
| May 8 | West Virginia Chaos | 0:3 | Ironbound Express | 7:00 |
| May 9 | West Virginia Chaos | 0:3 | New Jersey Rangers | 1:00 |
| May 9 | Hampton Roads Piranhas | 0:5 | Reading United AC | 6:30 |
| May 12 | Ironbound Express | 2:0 | Central Jersey Spartans | 8:00 |
| May 14 | Northern Virginia Royals | 1:3 | Reading United AC | 7:30 |
| May 15 | Ironbound Express | 1:0 | New Jersey Rangers | 4:30 |
| May 15 | Hampton Roads Piranhas | 2:2 | Ocean City Nor’easters | 7:00 |
| May 15 | Central Jersey Spartans | 1:1 | Carolina Dynamo | 7:30 |
| May 19 | Ocean City Nor’easters | 0:3 | Ironbound Express | 8:00 |
| May 20 | Reading United AC | 1:0 | West Virginia Chaos | 7:30 |
| May 22 | New Jersey Rangers | 1:0 | Hampton Roads Piranhas | 5:30 |
| May 22 | Northern Virginia Royals | 1:1 | Ocean City Nor’easters | 7:00 |
| May 22 | Reading United AC | 4:0 | Carolina Dynamo | 7:30 |
| May 22 | Central Jersey Spartans | 0:2 | West Virginia Chaos | 7:30 |
| May 23 | New Jersey Rangers | 3:2 | Northern Virginia Royals | 7:00 |
| May 26 | Ocean City Nor’easters | 1:2 | Central Jersey Spartans | 7:30 |
| May 29 | Carolina Dynamo | 6:1 | Northern Virginia Royals | 7:30 |
| May 30 | Carolina Dynamo | 4:1 | Hampton Roads Piranhas | 8:00 |
| NORTHEAST DIVISION | GP | W | L | T | PTS | GF | GA | GF | GD | |
| Long Island Rough Riders | 4 | 3 | 0 | 1 | 10 | 9 | 2 | 6 | +5 | |
| Albany BWP Highlanders | 4 | 3 | 0 | 1 | 10 | 10 | 6 | 9 | +4 | |
| Western Mass Pioneers | 4 | 2 | 1 | 1 | 7 | 7 | 3 | 6 | +3 | |
| MPS Portland Phoenix | 4 | 1 | 0 | 3 | 6 | 6 | 3 | 6 | +3 | |
| New Hampshire Phantoms | 4 | 1 | 1 | 2 | 5 | 3 | 2 | 3 | +1 | |
| Vermont Voltage | 4 | 1 | 3 | 0 | 3 | 4 | 14 | 4 | -7 | |
| Westchester Flames | 4 | 0 | 2 | 2 | 2 | 2 | 6 | 2 | -4 | |
| Brooklyn Knights | 4 | 0 | 4 | 0 | 0 | 5 | 10 | 5 | -5 |
Top team qualifies for the US Open Cup
Clinched Open Cup berth – Eliminated from contention
Note: Columns on the far right are for tiebreaker purposes
USL Premier Development League tiebreakers
(1) Head-to-head record based on total points in Open Cup qualifiers
(2) Total wins in Open Cup qualifying games
(3) Goal difference (+/- 3 goals maximum for each USOC qualifier)
(4) Goals scored (+/- 3 goals maximum for each USOC qualifier)
(5) Lottery conducted by the USL
All times Eastern
| May 8 | Westchester Flames | 0:0 | New Hampshire Phantoms | 7:30 |
| May 9 | Westchester Flames | 0:3 | MPS Portland Phoenix | 4:00 |
| May 12 | Long Island Rough Riders | 1:0 | Brooklyn Knights | 8:00 |
| May 14 | MPS Portland Phoenix | 2:2 | Albany BWP Highlanders | 7:30 |
| May 15 | Albany BWP Highlanders | 1:0 | Western Mass Pioneers | 7:00 |
| May 15 | Vermont Voltage | 2:1 | Westchester Flames | 7:30 |
| May 16 | Western Mass Pioneers | 0:0 | MPS Portland Phoenix | 4:00 |
| May 16 | Vermont Voltage | 1:6 | Long Island Rough Riders | 6:00 |
| May 21 | Albany BWP Highlanders | 3:1 | Vermont Voltage | 7:30 |
| May 22 | Brooklyn Knights | 3:4 | Albany BWP Highlanders | 7:30 |
| May 22 | Western Mass Pioneers | 4:0 | Vermont Voltage | 7:30 |
| May 22 | New Hampshire Phantoms | 0:1 | Long Island Rough Riders | 7:30 |
| May 23 | New Hampshire Phantoms | 2:0 | Brooklyn Knights | 7:00 |
| May 28 | Western Mass Pioneers | 3:2 | Brooklyn Knights | 8:00 |
| May 29 | Long Island Rough Riders | 1:1 | Westchester Flames | 7:30 |
| May 29 | MPS Portland Phoenix | 1:1 | New Hampshire Phantoms | 7:30 |